Current issue

EDITORIAL JOURNAL OF AGING, RESEARCH & LIFESTYLE

Ara S. Khachaturian

J Aging Res & Lifestyle 2023;12:1-3

CITATION:
Ara S. Khachaturian ; (2023): Editorial: Journal of Aging, Research & LifeStyle. The Journal of Aging and Lifestyle (JARLife). http://dx.doi.org/10.14283/jarlife.2023.1

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DEPRESSIVE SYMPTOMS IN OLDER ADULTS VIA MULTIMODAL MARKERS ON MAGNETIC RESONANCE IMAGING: A LITERATURE REVIEW

M. Montoya-Martinez, C. Arbus, K. Virecoulon Giudici

J Aging Res & Lifestyle 2023;12:4-13

Depressive symptoms the most prevalent clinical condition in the field of mood disorders in older populations. Depressive symptoms are associated to poorer morbidity and mortality, and is considered a component of frailty and intrinsic capacity. Dementia could overlap with DS in clinical and brain abnormalities. Moreover, there are sex-differences in the field of Neuro- and Gero-science. To date, no review has addressed the neuro-anatomical basis of DS in older adults using magnetic resonance imaging (MRI), neither has investigated the discrimination of dementia nor sex-differences. This narrative review investigated studies about older adults; depressive symptoms evaluation via MRI, and published in English or Spanish over the past 7 years. Moreover, it evaluated dementia discrimination and sex-related differences. The most accurate evidence showed cerebral small vessel disease as a predictor of depressive symptoms worsening. Most studies were cross-sectional, with a coarse dementia screening and sex-unrepresentative samples. Cingulate cortex and hippocampus showed a negative association to depressive symptoms, and Precuneus cortex a positive association; although these inferences require further investigation. Additional research is needed to identify the brain imaging signature of depressive symptoms in older population (if any), and if this would be associated with sex and individuals’level of frailty and intrinsic capacity.

CITATION:
M. Montoya-Martinez ; C. Arbus ; K. Virecoulon Giudici ; (2023): Depressive Symptoms in Older Adults via Multimodal Markers on Magnetic Resonance Imaging: a Literature Review. The Journal of Aging and Lifestyle (JARLife). http://dx.doi.org/10.14283/jarlife.2023.2

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USING CLINICAL DECISION INTELLIGENCE APPLICATIONS TO IMPROVE PATHWAYS FOR EARLIER DETECTION OF UNDERRECOGNIZED COGNITIVE DISORDERS

A.S. Khachaturian, B. Cassin, G.R. Finney

J Aging Res & Lifestyle 2023;12:14-17

Cost estimates for care for those with dementia and other cognitive impairments are rising globally, estimated to reach US $1 trillion by 2025. Lack of specialized personnel, infrastructure, diagnostic capabilities, and healthcare access impedes the timely identification of patients progressing to dementia, particularly in underserved populations. International healthcare infrastructure may be unable to handle existing cases in addition to a sudden increase due to undiagnosed cognitive impairment and dementia. Healthcare bioinformatics offers a potential route for quicker access to healthcare services; however, a better preparedness plan must be implemented now if expected demands are to be met. The most critical consideration for implementing artificial intelligence/machine learning (AI/ML) -driven clinical decision intelligence applications (CDIA) is ensuring patients and practitioners take action on the information provided.

CITATION:
A.S. Khachaturian ; B. Cassin ; G.R. Finney ; (2023): Using Clinical Decision Intelligence Applications to Improve Pathways For Earlier Detection Of Underrecognized Cognitive Disorders. The Journal of Aging and Lifestyle (JARLife). http://dx.doi.org/10.14283/jarlife.2023.3

EDITORIAL: HOW TO IMPLEMENT INTEGRATED CARE FOR OLDER PERSONS—ICOPE— MASSIVELY IN CLINICAL PRACTICE FOR A HEALTHY LONGEVITY

B. Vellas

J Aging Res & Lifestyle 2023;12:18-19