journal articles
TEMPORAL MUSCLE THICKNESS PREDICTS CHANGE IN NUTRITIONAL MARKERS IN INDIVIDUALS AT RISK OF DEMENTIA: INSIGHTS FROM A 24-WEEK LONGITUDINAL STUDY
Salomón Salazar-Londoño, Valeria Pérez-Foucrier, Jonathan Patricio Baldera, Markus Aarsland, Luis Carlos Venegas-Sanabria, Miguel German Borda, NJ FINGER
J Aging Res & Lifestyle 2025;14
OBJEVTIVES: To investigate whether temporal muscle thickness (TMT) can serve as a predictor of change in nutritional widely used biomarkers in patients at risk of dementia.
DESIGN: Longitudinal observational study.
SETTING: Secondary analysis from a 24-week study conducted across three centers in Norway between 2018 and 2020.
PARTICIPANTS: Patients with mild cognitive impairment (MCI) or with two cardiometabolic disorders were included (n = 165).
MEASUREMENTS: Baseline and longitudinal statistical analysis were carried out to establish the association for outcomes (albumin, weight, C-Reactive Protein and Episodic Memory Quality) with TMT.
RESULTS: At baseline, there was a positive association between TMT and weight (Estimate=1.5157, p = 0.009). At follow-up, positive associations were observed between TMT and albumin levels (Estimate=0.3031, P = 0.048), as well as TMT and weight (Estimate=1.8954, P = 0.001).
CONCLUSIONS: TMT is a possible accessible tool in clinical practice for monitoring health variables beyond cognitive decline in patients at risk of dementia.
CITATION:
Salomón Salazar-Londoño ; Valeria Pérez-Foucrier ; Jonathan Patricio Baldera ; Markus Aarsland ; Luis Carlos Venegas-Sanabria ; Miguel German Borda ; NJ FINGER (2025): Temporal muscle thickness predicts change in nutritional markers in individuals at risk of dementia: Insights from a 24-week longitudinal study. The Journal of Aging and Lifestyle (JARLife). https://doi.org/10.1016/j.jarlif.2025.100023