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INTENSIVE GLUCOSE CONTROL IN THE TREATMENT OF HYPERGLYCEMIA IN PATIENTS WITH AN ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A PROSPECTIVE STUDY

L. Gao, H. Ren, Q. Hao

J Aging Res Clin Practice 2014;3(3):159-162

Background and Objective: This study was conducted to evaluate the influence of IGC in the treatment of hyperglycemia combined with AECOPD. Methods: A total of 267 consecutively hospitalized patients with AECOPD combined with hyperglycemia in the general wards of the East Ward of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital and West China Hospital from May 2007 to August 2013 were included in this study. All the patients were allocated to either the IGC group or the control group according to the doctor’s recommendation. The short-term mortality rate as well as the duration and medical cost of the hospitalization were investigated. Results: The median length of the hospital stay was 15 days in the IGC group, whereas the median was 12 days (p=0.05) in the control group. The median medical cost was 8,866 Yuan in the IGC group, whereas this value was 8,051 Yuan in the control group. However, the medical costs, the mortality rates and the positive sputum culture rates were not statistically different between the two groups. There were more cases of hypoglycemia and hypokalemia in the IGC group than in the control group. Conclusions: Intensive glucose control treatment did not result in any benefits in the patients with hyperglycemia and AECOPD and may prolong the length of stay and increase the risk of hypoglycemia and hypokalemia.

CITATION:
L. Gao ; H. Ren ; Q. Hao (2014): INTENSIVE GLUCOSE CONTROL IN THE TREATMENT OF HYPERGLYCEMIA IN PATIENTS WITH AN ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A PROSPECTIVE STUDY . The Journal of Aging Research and Clinical Practice (JARCP). http://dx.doi.org/10.14283/jarcp.2014.27

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